• Title of article

    Cytotoxic trichilin-type limonoids from Melia azedarach Original Research Article

  • Author/Authors

    Koichi Takeya، نويسنده , , Zhi-Sheng Qiao، نويسنده , , Chieko Hirobe، نويسنده , , Hideji Itokawa، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 1996
  • Pages
    5
  • From page
    1355
  • To page
    1359
  • Abstract
    Five new trichilin-type limonoids, named 12-deacetyltrichilin 1 (1), 1-acetyltrichilin H (2), 3-deacetyltrichilin H (3), 1-acetyl-3-deacetyltrichilin H (4), 1-acetyl-2-deacetyltrichilin H (5), together with four known trichilins, meliatoxin B1 (6), trichilin H (7), trichilin D (8) and 1,12-diacetyltrichilin B (9) were isolated from the extract of the root bark of Melia azedarach. The structures were elucidated by spectroscopic means and their cytotoxic activities against P388 cells in vitro were tested by means of MTT assay.
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Serial Year
    1996
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Record number

    1300892