Title of article
Taxus canadensis abundant taxane: conversion to paclitaxel and rearrangements Original Research Article
Author/Authors
Anastasia Nikolakakis، نويسنده , , Gaétan Caron، نويسنده , , Alice Cherestes، نويسنده , , Françoise Sauriol، نويسنده , , Orval Mamer، نويسنده , , Lolita O Zamir، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2000
Pages
12
From page
1269
To page
1280
Abstract
An efficient conversion of Taxus canadensis abundant taxane, 9-dihydro-13-acetylbaccatin III to baccatin III is described. Since the synthesis of paclitaxel from baccatin III has been reported, this work can be used for additional supply of this powerful anticancer drug. In addition, new taxanes derived from skeletal rearrangements originating from oxidation–reduction reactions of the Canadian yew major taxane, are reported.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2000
Journal title
Bioorganic and Medicinal Chemistry
Record number
1301036
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