Title of article
3N-Methylbiphenylsulfonylurea and -carbamate substituted imidazo[4,5-b]pyridines. Potent antagonists of the ANG II AT1 receptors Original Research Article
Author/Authors
Holger Heitsch، نويسنده , , Reinhard H.A. Becker، نويسنده , , Heinz-Werner Kleemann، نويسنده , , Adalbert Wagner، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
673
To page
678
Abstract
The synthesis and the SAR study of imidazo[4,5-b]pyridine biphenyl sulfonylureas and -carbamates as highly potent AT1-selective ANG II receptor antagonists are described. Several members of this new class of antagonists efficiently inhibited the ANG II-induced pressor response in pithed rats after iv and intraduodenal (id) administration.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1997
Journal title
Bioorganic and Medicinal Chemistry
Record number
1301160
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