Author/Authors :
Ulrike Gambert، نويسنده , , Raul Gonzalez Lio، نويسنده , , Erzsébet Farkas، نويسنده , , Joachim Thiem، نويسنده , , Vicente Verez-Bencomo، نويسنده , , Andr?s Lipt?k، نويسنده ,
Abstract :
In this study β1–3 linked analogues of the T-antigen determinant were synthesized in preparative scale by transgalactosylation using β-galactosidase from bovine testes to give synthetic antigens. Acceptors with modifications of the sugar residue such as α-glycosylated spacers, as well as GlcNAc-αOR- and 2dGal-αOR-substrates opened further possibilities for galactosylation.