Title of article
Immunostimulatory activities of mono- or diglycosylated α-galactosylceramides Original Research Article
Author/Authors
Akira Uchimura، نويسنده , , Toshiyuki Shimizu، نويسنده , , Miiko Nakajima، نويسنده , , Hitomi Ueno، نويسنده , , Kazuhiro Motoki، نويسنده , , Hideaki Fukushima، نويسنده , , Takenori Natori، نويسنده , , Yasuhiko Koezuka، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1997
Pages
6
From page
1447
To page
1452
Abstract
We examined the effects of 2″- or 3″-monoglycosylated α-galactosylceramides (α-GalCers) and 2″,3″-diglycosylated α-GalCers on allogeneic MLR and the proliferation of murine spleen cells. It was found that their ceramide portions greatly affect their immunostimulatory activities, and that the 3″-hydroxyl group plays a more important role in the immunostimulatory effects of α-GalCer derivatives than the 2″-hydroxyl group.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1997
Journal title
Bioorganic and Medicinal Chemistry
Record number
1301272
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