• Title of article

    Design, synthesis and preliminary biological evaluation of a focused combinatorial library of stereodiverse carbohydrate-scaffold-based peptidomimetics Original Research Article

  • Author/Authors

    Nicolas Moitessier، نويسنده , , Sylvie Dufour، نويسنده , , Françoise Chrétien، نويسنده , , Jean Paul Thiery، نويسنده , , Bernard Maigret، نويسنده , , Yves Chapleur، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2001
  • Pages
    13
  • From page
    511
  • To page
    523
  • Abstract
    A focused combinatorial library of 126 mimetics of the RGD sequence based on sugar scaffolds have been rationally constructed using molecular modeling, with a particular emphasis on the stereodiversity of the library. A liquid phase, mix and divide synthesis was used, active compounds being identified by using orthogonal libraries and recursive deconvolution strategies.
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Serial Year
    2001
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Record number

    1301377

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1301377