Author/Authors :
Susumu Ito، نويسنده , , Naoki Muguruma، نويسنده , , Shigehito Hayashi، نويسنده , , Satoko Taoka، نويسنده , , Terumi Bando، نويسنده , , Kumi Inayama، نويسنده , , Masahiro Sogabe، نويسنده , , Toshiya Okahisa، نويسنده , , Seisuke Okamura، نويسنده , , Hiroshi Shibata، نويسنده , , Tatsuro Irimura، نويسنده , , Kazuhiro Takesako، نويسنده , , Seiichi Shibamura، نويسنده ,
Abstract :
Fluorescence intensity of indocyanine green (ICG) derivative (ICG-sulfo-OSu) was too low for its use to detect microlesions. Therefore, we examined the effects of reinforcement agents on ICG-sulfo-OSu labeled antibodies. Solutions of distearoylphosphatic acid sodium salt (DSPA) and octylglucoside (OG) in physiological phosphate buffered saline (PBS) were found to increase the intensity of fluorescence of ICG-sulfo-OSu labeled antibodies, with shift in the fluorescence peak wavelength from 804 to 821 nm.
Keywords :
fluorescence , Reinforcement agents , distearoylphosphatidic acid sodium salt (DSPA) , octylglucoside (OG) , infrared rays
