Title of article :
Mechanism of Biochemical Action of Substituted 4-Methylbenzopyran-2-ones. Part I: Dioxygenated 4-Methyl Coumarins as Superb Antioxidant and Radical Scavenging Agents Original Research Article
Author/Authors :
Hanumantharao G. Raj، نويسنده , , Virinder S. Parmar، نويسنده , , Subhash C. Jain، نويسنده , , Sanjay Goel، نويسنده , , Poonam Himanshu، نويسنده , , Sanjay Malhotra، نويسنده , , Amarjit Singh، نويسنده , , Carl E Olsen، نويسنده , , Jesper Wengel، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Pages :
7
From page :
833
To page :
839
Abstract :
Twenty-three 4-methylcoumarins bearing different functionalities have been examined for the first time for their effect on NADPH-catalysed liver-microsomal lipid peroxidation with a view to establish structure–activity relationship. Dihydroxy- and diacetoxy-4-methylcoumarins produced dramatic inhibition of lipid peroxidation. 7,8-Diacetoxy-4-methylcoumarin and 7,8-dihydroxy-4-methylcoumarin were found to possess superb antioxidant and radical scavenging activities.
Journal title :
Bioorganic and Medicinal Chemistry
Serial Year :
1998
Journal title :
Bioorganic and Medicinal Chemistry
Record number :
1301579
Link To Document :
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