Title of article
In search of novel water soluble forskolin analogues for positive inotropic activity Original Research Article
Author/Authors
Sanjay Arora, Bansi Lal، نويسنده , , Ashok Kumar Gangopadhyay، نويسنده , , Ramesh M. Gidwani، نويسنده , , Magno Fernandes، نويسنده , , Ramanujam Rajagopalan، نويسنده , , Anil Vasantrao Ghate، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 1998
Pages
9
From page
2075
To page
2083
Abstract
Using the novel lead from hydroxy acetyl substituted forskolin analogues, such as 7β-hydroxyacetyl-7β-deacetyl forskolin or 6β-hydroxyacetyl forskolin, a number of water soluble ω-amino acyl derivatives were synthesized. Two such compounds 6 and 18 showed better in vitro activity but failed to show in vivo activity.
Keywords
Forskolin , 2-hydroxy acetyl , ?-aminoacyl , positive inotropic activity
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
1998
Journal title
Bioorganic and Medicinal Chemistry
Record number
1301808
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