Title of article :
Synthesis, cytotoxic activity, NMR study and stereochemical effects of some new pyrano[3,2-b]thioxanthen-6-ones and Pyrano[2,3-c]thioxanthen-7-ones Original Research Article
Author/Authors :
Ioannis K. Kostakis، نويسنده , , Nicole Pouli، نويسنده , , Panagiotis Marakos، نويسنده , , Emmanuel Mikros، نويسنده , , Alexios-Leandros Skaltsounis، نويسنده , , Stephane Leonce، نويسنده , , Ghanem Atassi، نويسنده , , Pierre Renard، نويسنده ,
Abstract :
Some new substituted pyrano[3,2-b]thioxanthen-6-ones and pyrano[2,3-c]thioxanthen-7-ones were prepared and their cytotoxic activity was evaluated using acronycine as the reference compound. The conformation of the molecules was also investigated in an effort to correlate this parameter with the biological activity.