Title of article :
The design, synthesis, and evaluation of novel conformationally rigid analogues of sialyl Lewisx Original Research Article
Author/Authors :
Paul V. Murphy، نويسنده , , Rod E. Hubbard، نويسنده , , David T. Manallack، نويسنده , , Ruth E. Wills، نويسنده , , John G. Montana، نويسنده , , Richard J.K. Taylor، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Abstract :
The design and synthesis of a series of analogues of sialyl Lewisx (1) which incorporate conformationally rigid tetralin and naphthalene ring systems (2–4) has led to novel compounds which have similar potency to 1 as inhibitors of cell adhesion.
Keywords :
Cell adhesion , selectin inhibitors , Tetralins , Sialyl Lewisx , naphthalenes.
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
