Author/Authors :
Shiroh Futaki، نويسنده , , Mika Aoki-Suzuki، نويسنده , , Tomoko Ishikawa، نويسنده , , Fusayo Kondo، نويسنده , , Tomoko Asahara، نويسنده , , Mineo Niwa، نويسنده , , Yutaka Nakaya، نويسنده , , Takeshi Yagami، نويسنده , , Kouki Kitagawa، نويسنده ,
Abstract :
Development of the strategies for assembling multiple kinds of peptide segments would give new possibilities for the de novo design of functional proteins. We will introduce our approach for the selective assembly of helical peptide segments on a peptide template to give four-helix-bundle proteins comprising individual helices.
Keywords :
de novo design , helix-bundle protein , chemical ligation , artificial protein , Peptide synthesis