A mercapto analogue of 5′-noraristeromycin Original Research Article

5′-Noraristeromycin () and its enantiomer () have been found to possess a wide range of antiviral effects. In the search for analogues of and with improved activity, the synthesis of both enantiomers of 5′-mercapto-5′-deoxy-5′-noraristeromycin ( and ) has been accomplished. While (+)-7 was inactive, (−)- did show marginal activity against vaccinia virus, but not any other virus.