Title of article
Baylis–Hillman Reaction: Convenient Ascending Syntheses and Biological Evaluation of Acyclic Deoxy Monosaccharides as Potential Antimycobacterial Agents Original Research Article
Author/Authors
Rashmi Pathak، نويسنده , , Chandra Shekhar Pant، نويسنده , , Arun K. Shaw، نويسنده , , Amiya P Bhaduri، نويسنده , , Anil N Gaikwad، نويسنده , , Sudhir Sinha، نويسنده , , Anil Srivastava، نويسنده , , Kishore K. Srivastava، نويسنده , , Vinita Chaturvedi، نويسنده , , Ranjana Srivastava، نويسنده , , Brahm S. Srivastava، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
10
From page
3187
To page
3196
Abstract
A series of acyclic deoxy carbohydrate derivatives from easily available carbohydrate enals 1, 2, 3 or 5 were prepared involving the Baylis–Hillman reaction. These newly formed carbohydrate based Baylis–Hillman adducts and their amino derivatives were evaluated for their antimycobacterial activity against Mycobacterium tuberculosis H37Rv. Among the compounds evaluated for their antimycobacterial activity, compound (10) showed the desired activity in the range of 3.125 μg/mL.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2002
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302254
Link To Document