Title of article :
d-Glucosamine propanedithioacetal, an efficient chiral auxiliary in β-Lactam chemistry Original Research Article
Author/Authors :
Josefa Anaya، نويسنده , , Stéphane Dov Gero، نويسنده , , Manuel Grande، نويسنده , , José Ignacio M Hernando، نويسنده , , Nieves M Laso، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1999
Abstract :
The synthesis of some monocyclic β-lactams (monobactams) by the Staudinger reaction using d-glucosamine propanedithioacetal as chiral auxiliary is reported. The influence of several radicals at C3, C4, and C1′ (sugar moiety) as well as other structural aspects are considered in relation to the antielastase activity.
Keywords :
Synthesis , structure/circular dichroism , antielastase activity , ?-Lactams
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
