Synthesis and biological evaluation of novel turn-modified gramicidin S analogues Original Research Article
Author/Authors :
Gijsbert M. Grotenbreg، نويسنده , , Emile Spalburg، نويسنده , , Albert J de Neeling، نويسنده , , Gijsbert A. van der Marel، نويسنده , , Herman S. Overkleeft، نويسنده , , Jacques H. van Boom، نويسنده , , Mark Overhand، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Pages :
7
From page :
2835
To page :
2841
Abstract :
The synthesis of novel gramicidin S analogues having additional functionalities in the turn region by employing a biomimetic approach is described. The preservation of β-sheet character in all analogues was established by NMR and the biological activity was evaluated.
