Title of article
Studies on the interaction of the antibiotic moenomycin A with the enzyme penicillin-binding protein 1b Original Research Article
Author/Authors
Thomas Rühl، نويسنده , , Mohammed Daghish، نويسنده , , Andrij Buchynskyy، نويسنده , , Karen Barche، نويسنده , , Daniela Volke، نويسنده , , Katherina Stembera، نويسنده , , Uwe Kempin، نويسنده , , Dietmar Knoll، نويسنده , , Lothar Hennig، نويسنده , , Matthias Findeisen، نويسنده , , Ramona Oehme، نويسنده , , Sabine Giesa، نويسنده , , Juan Ayala، نويسنده , , Peter Welzel، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
17
From page
2965
To page
2981
Abstract
The interaction of a moenomycin derivative with the enzyme penicillin binding protein 1b (PBP 1b) has been studied by means of STD NMR. The results obtained initiated the synthesis of a number of moenomycin derivatives modified in unit A including a moenomycin–ampicillin conjugate and determination of their antibiotic activities. A protocol is described that allows studying the interaction of moenomycin analogues with PBP 1b by fluorescence correlation spectroscopy.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2003
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302770
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