Author/Authors :
Sunil K. Chattopadhyay، نويسنده , , T.R.Santha Kumar، نويسنده , , Prakas R. Maulik، نويسنده , , Sachin Srivastava، نويسنده , , Ankur Garg، نويسنده , , Ashoke Sharon، نويسنده , , Arvind S Negi، نويسنده , , Suman Preet S. Khanuja، نويسنده ,
Abstract :
Absolute configuration of taxiresinol 1, a lignan from the heartwood of Taxus wallichiana has been determined as 8R, 8′R, and 7′R with the help of chemical correlation method and X-ray crystallography. The anticancer activity of taxiresinol 1 and other two lignans 2, 3 were also studied. Taxiresinol 1 showed notable anticancer activity in the in vitro bioassays against colon, liver, ovarian and breast cancer cell lines.
