Title of article
Absolute configuration and anticancer activity of taxiresinol and related lignans of Taxus wallichiana Original Research Article
Author/Authors
Sunil K. Chattopadhyay، نويسنده , , T.R.Santha Kumar، نويسنده , , Prakas R. Maulik، نويسنده , , Sachin Srivastava، نويسنده , , Ankur Garg، نويسنده , , Ashoke Sharon، نويسنده , , Arvind S Negi، نويسنده , , Suman Preet S. Khanuja، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
4945
To page
4948
Abstract
Absolute configuration of taxiresinol 1, a lignan from the heartwood of Taxus wallichiana has been determined as 8R, 8′R, and 7′R with the help of chemical correlation method and X-ray crystallography. The anticancer activity of taxiresinol 1 and other two lignans 2, 3 were also studied. Taxiresinol 1 showed notable anticancer activity in the in vitro bioassays against colon, liver, ovarian and breast cancer cell lines.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2003
Journal title
Bioorganic and Medicinal Chemistry
Record number
1302811
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