Title of article :
Synthesis and antihyperglycemic activity of chalcone based aryloxypropanolamines Original Research Article
Author/Authors :
M Satyanarayana، نويسنده , , Priti Tiwari، نويسنده , , Brajendra K. Tripathi، نويسنده , , A.K Srivastava، نويسنده , , Ram Pratap، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
A series of aryloxypropanolamines (5a–r) of different chalcones (3a–e) were synthesized and evaluated for antihyperglycemic activity in sucrose loaded (SLM) and streptozotocin (STZ) induced diabetic animal models. Among them compounds 5a, g, m, o, p and r showed significant reduction in blood glucose levels in both SLM and STZ animal models.
Keywords :
Chalcones , Aryloxypropanolamines and antihyperglycemic activity
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
