Title of article :
Natural product glycorandomization
Author/Authors :
Jie Yang، نويسنده , , Dirk Hoffmeister، نويسنده , , Lesley Liu، نويسنده , , Xun Fu، نويسنده , , Jon S. Thorson، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
Glycorandomization is a chemoenzymatic strategy that overcomes the limitations in natural product derivatization associated with both solely chemistry-based approaches or in vivo engineering. In this article we present the basic strategies for glycorandomization development as a next-generation tool in drug discovery.
Keywords :
Glycosyltransferase , Enzyme catalysis , Galactokinase , Nucleotidylyltransferase , Natural products , Antibiotics
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
