Title of article
QSAR study on phenolic activity: need of positive hydrophobic term (logP) in QSAR Original Research Article
Author/Authors
Mamta Thakur، نويسنده , , Alok Agarwal، نويسنده , , Abhilash Thakur، نويسنده , , Keshav C. Mathur and Padmakar V. Khadikar، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
7
From page
2287
To page
2293
Abstract
The phenolic activity (log1/C) of a large series of phenols against L1210 leukaemia cells was modelled using physicochemical parameters other than conventional electronic and steric parameters. Attempts have also been made to examine need or otherwise of the hydrophobic parameter, logP, in such studies. The results have shown that contribution of logP in modelling log1/C is favourable.
Keywords
QSAR , Leukaemia , Regression analysis , Hydrophobicity/lipophilicity , Molecular descriptors , Phenols
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2004
Journal title
Bioorganic and Medicinal Chemistry
Record number
1303036
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