Title of article
QSPR of 3-aryloxazolidin-2-one antibacterials Original Research Article
Author/Authors
Alan R. Katritzky، نويسنده , , Dan C. Fara، نويسنده , , Mati Karelson، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2004
Pages
9
From page
3027
To page
3035
Abstract
A QSPR treatment has been applied to a data set consisting of 60 3-aryloxazolidin-2-one antibacterials to relate the in vitro minimum inhibitory concentration (MIC) (required to inhibiting growth of S. aureus) with theoretical molecular and fragment descriptors. The treatment using codessa pro descriptors leads to a seven-parameter model with r2=0.820 and r2cv=0.758.
Keywords
QSPR/QSAR , Antibacterials , Molecular descriptors , CODESSA PRO
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2004
Journal title
Bioorganic and Medicinal Chemistry
Record number
1303107
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