Title of article :
Synthesis and DNA binding affinity of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers Original Research Article
Author/Authors :
Ahmed Kamal، نويسنده , , O Srinivas، نويسنده , , P Ramulu، نويسنده , , G Ramesh، نويسنده , , P.Praveen Kumar، نويسنده , , M.Shiva Kumar، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
The synthesis of novel A-C8/C-C2-exo unsaturated alkoxyamido-linked pyrrolo[2,1-c][1,4]benzodiazepine dimers is reported and these dimers show significant DNA binding affinity and they also exhibit moderate anticancer activity.
Keywords :
DNA binding affinity , Cytotoxicity , Pyrrolobenzodiazepine dimers
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
