• Title of article

    Second-generation dimeric inhibitors of chitin synthase Original Research Article

  • Author/Authors

    Adam R. Yeager، نويسنده , , Nathaniel S. Finney، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2004
  • Pages
    10
  • From page
    6451
  • To page
    6460
  • Abstract
    Chitin synthase (CS) is essential for fungal cell wall biosynthesis and is an attractive medicinal target. Expanded results from our efforts to develop mechanism based inhibitors of CS are presented here. Specifically, we describe uridine dimers linked by tartrate amides as potential pyrophosphate mimics.
  • Keywords
    Glycosyltransferase , Mechanism , Inhibitor , Phosphate mimic
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Serial Year
    2004
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Record number

    1303407

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1303407