Title of article
New sesquiterpene from Vietnamese agarwood and its induction effect on brain-derived neurotrophic factor mRNA expression in vitro Original Research Article
Author/Authors
Junya Ueda، نويسنده , , Lisa Imamura، نويسنده , , Yasuhiro Tezuka، نويسنده , , Quan L. Tran، نويسنده , , Masaaki Tsuda، نويسنده , , Shigetoshi Kadota، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
4
From page
3571
To page
3574
Abstract
Agarwood, one of the valuable non-timber products in tropical forest, is a fragrant wood, whose ethereal fragrance has been prized in Asia for incense in ceremony, as well as sedatives in traditional medicine. We separated the 70% EtOH extract of Vietnamese agarwood, which showed significant induction effect on brain-derived neurotrophic factor (BDNF) mRNA expression in rat cultured neuronal cells, to isolate a new compound and a 2-(2-phenylethyl)chromone derivative. The new compound was determined to be a spirovetivane-type sesquiterpene, (4R,5R,7R)-1(10)-spirovetiven-11-ol-2-one, by spectroscopic data and showed induction effect of BDNF mRNA.
Keywords
Agarwood , Tram , Vietnamese , Spirovetivane-type sesquiterpene , 2-(2-Phenylethyl)chromone derivative , Brain-derived neurotrophic factor
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2006
Journal title
Bioorganic and Medicinal Chemistry
Record number
1303432
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