Title of article :
Achiral, selective CCK2 receptor antagonists based on a 1,3,5-benzotriazepine-2,4-dione template Original Research Article
Author/Authors :
John Spencer ، نويسنده , , John Gaffen، نويسنده , , Eric Griffin، نويسنده , , Elaine A. Harper، نويسنده , , Ian D. Linney، نويسنده , , Iain M. McDonald، نويسنده , , Sonia P. Roberts، نويسنده , , Mark E. Shaxted، نويسنده , , Trushar Adatia، نويسنده , , Alan Bashall، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
Novel, achiral 1H-1,3,5-benzotriazepine-2,4(3H,5H)-diones have been prepared and structurally characterized. These compounds are potent CCK2 receptor antagonists that display a high degree of selectivity over CCK1 receptors.
Keywords :
Antagonist , Benzotriazepine , CCK , CCK2 , Gastrin
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
