Author/Authors :
Robert Musiol، نويسنده , , Dominik Tabak، نويسنده , , Halina Niedbala، نويسنده , , Barbara Podeszwa، نويسنده , , Josef Jampilek، نويسنده , , Katarina Kralova، نويسنده , , Jiri Dohnal، نويسنده , , Jacek Finster، نويسنده , , Agnieszka Mencel، نويسنده , , Jaroslaw Polanski، نويسنده ,
Abstract :
Two series of amides based on quinoline scaffold were designed and synthesized in search of photosynthesis inhibitors. The compounds were tested for their photosynthesis-inhibiting activity against Spinacia oleracea L. and Chlorella vulgaris Beij. The compounds lipophilicity was determined by the RP-HPLC method. Several compounds showed biological activity similar or even higher than that of the standard (DCMU). The structure–activity relationships are discussed.
Keywords :
Lipophilicity , PET inhibition , Spinach chloroplasts , Chlorophyll , Chlorella vulgaris , Quinoline derivatives