Title of article :
Synthesis and anti-HIV1 biological activity of novel 5″-ATSAO compounds Original Research Article
Author/Authors :
Cyrille Tomassi، نويسنده , , Albert Nguyen van Nhien، نويسنده , , José Marco-Contelles، نويسنده , , Jan Balzarini، نويسنده , , Christophe Pannecouque، نويسنده , , Erik De Clercq، نويسنده , , Denis Postel، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2008
Abstract :
Aza TSAO-T derivatives bearing a substituted dihydroisothiazole dioxide ring with a phenyl group at 5″ position were prepared. Biological evaluation showed that phenyl group gives rise to a dramatical decrease of the inhibitory effect.
Keywords :
Glycoaminonitrile , ATSAO , TSAO , NNRTI , CSIC reaction
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
