Title of article
Cytotoxicity of abietane diterpenoids from Perovskia abrotanoides and of their semisynthetic analogues Original Research Article
Author/Authors
Yutaka Aoyagi، نويسنده , , Yoshinao Takahashi، نويسنده , , Yudai Satake، نويسنده , , Koichi Takeya، نويسنده , , Ritsuo Aiyama، نويسنده , , Takeshi Matsuzaki، نويسنده , , Shusuke Hashimoto، نويسنده , , Teruo Kurihara، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
7
From page
5285
To page
5291
Abstract
Seven known abietane diterpenoids and 11-O- and 12-O-acetylcarnosic acids were isolated from a methanol extract of Perovskia abrotanoides (Labiatae). Structure and cytotoxic activity relationships (SAR) of the natural and semisynthetic analogues of the presently isolated abietane diterpenoids were studied by using P388 murine leukemia cells.
Keywords
Carnosic acid , P388 murine leukemia cells , Semisynthesis , Cytotoxicity , Abietane diterpenoids , SAR
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2006
Journal title
Bioorganic and Medicinal Chemistry
Record number
1304532
Link To Document