Title of article
Caulerpenyne–colchicine hybrid: Synthesis and biological evaluation Original Research Article
Author/Authors
Julien Bourdron، نويسنده , , Laurent Commeiras، نويسنده , , Pascale Barbier، نويسنده , , Véronique Bourgarel-Rey، نويسنده , , Eddy Pasquier، نويسنده , , Nicolas Vanthuyne، نويسنده , , Jean Claude Hubaud، نويسنده , , Vincent Peyrot، نويسنده , , Jean-Luc Parrain، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
9
From page
5540
To page
5548
Abstract
The synthesis of an analog of caulerpenyne having a trimethoxyaryl moiety was achieved in 11% overall yield over 11 steps. Its biological activity has been evaluated as inhibitor of in vitro tubulin polymerization or angiogenesis.
Keywords
tubulin polymerization , caulerpenyne , Cell cytotoxicity , In vitro angiogenesis , Colchicine , Biological evaluation
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2006
Journal title
Bioorganic and Medicinal Chemistry
Record number
1304559
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