Title of article
Protein linear indices of the ‘macromolecular pseudograph α-carbon atom adjacency matrix’ in bioinformatics. Part 1: Prediction of protein stability effects of a complete set of alanine substitutions in Arc repressor Original Research Article
Author/Authors
Yovani Marrero-Ponce، نويسنده , , Ricardo Medina-Marrero، نويسنده , , Juan A. Castillo-Garit، نويسنده , , Vicente Romero-Zaldivar، نويسنده , , Francisco Torrens، نويسنده , , Eduardo A. Castro، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2005
Pages
13
From page
3003
To page
3015
Abstract
A novel approach to bio-macromolecular design from a linear algebra point of view is introduced. A protein’s total (whole protein) and local (one or more amino acid) linear indices are a new set of bio-macromolecular descriptors of relevance to protein QSAR/QSPR studies. These amino-acid level biochemical descriptors are based on the calculation of linear ma
Keywords
protein stability , Arc repressor , Alanine-substitution mutant , TOMOCOMD-CAMPS software , Protein linear indices , QSAR
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2005
Journal title
Bioorganic and Medicinal Chemistry
Record number
1304653
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