Synthesis of aromatic C-xylosides by position inversion of glucose Original Research Article

Two formally C-xylosylated analogs to 2-naphthyl β-d-xylopyranoside, which is known to initiate priming of glucosaminoglycan chains, were synthesized by a position inversion of glucose (i.e., position 1 becomes position 5). The d-C-xyloside showed priming, while the l-C-xyloside did not initiate priming.