Title of article
Synthesis and evaluation of azaindole-α-alkyloxyphenylpropionic acid analogues as PPARα/γ agonists Original Research Article
Author/Authors
Zhefeng Cai، نويسنده , , Jun Feng، نويسنده , , Yanshen Guo، نويسنده , , Pingping Li، نويسنده , , Zhufang Shen، نويسنده , , Fengming Chu، نويسنده , , Zongru Guo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
9
From page
866
To page
874
Abstract
A series of azaindole-α-alkyloxyphenylpropionic acid analogues was synthesized and evaluated for PPAR agonist activities. Structure–activity relationship was developed for PPARα/γ dual agonism. One of the synthesized compound 7a was identified as a potent, selective PPARα/γ dual agonist.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2006
Journal title
Bioorganic and Medicinal Chemistry
Record number
1305164
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