Title of article :
Synthesis and biological activity of Schiff and Mannich bases bearing 2,4-dichloro-5-fluorophenyl moiety Original Research Article
Author/Authors :
Mari Sithambaram Karthikeyan، نويسنده , , Dasappa Jagadeesh Prasad، نويسنده , , Boja Poojary، نويسنده , , K. Subrahmanya Bhat، نويسنده , , Bantwal Shivarama Holla، نويسنده , , Nalilu Suchetha Kumari، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A series of 2,4-dichloro-5-fluorophenyl bearing Mannich base (4 and 5) was prepared from triazole Schiff bases (3) by aminomethylation with formaldehyde and secondary/substituted primary amines. All newly synthesized compounds were screened for their antimicrobial activity. Compounds 3c, 4c, 4e and 4f exhibited promising antibacterial and compounds 3c, 5c, 5e and 5f showed good antifungal activity.
Keywords :
4-Dichloro-5-fluorophenyl triazole , 2 , Schiff base , Antibacterial , Antifungal activity , Mannich base
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
