Title of article
Design of endoperoxides with anti-Candida activity Original Research Article
Author/Authors
Thomas D. Avery، نويسنده , , Peter I. Macreadie، نويسنده , , Ben W. Greatrex، نويسنده , , Tony V. Robinson، نويسنده , , Dennis K. Taylor، نويسنده , , Ian G. Macreadie، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
7
From page
36
To page
42
Abstract
Broad antifungal structure–activity relationships governing epoxy-endoperoxides 2 and 3 and their parent endoperoxides 1 are reported. Their inhibitory activity against Candida albicans in conjunction with hemolytic activity and/or growth inhibition of cultured mammalian cells are reported. This information provided guidance for the further development of endoperoxide and epoxy-endoperoxides as topical antifungal agents.
Keywords
Artemisinin , Endoperoxide , Candida , Growth inhibition , Antifungal , Hemolytic activity
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2007
Journal title
Bioorganic and Medicinal Chemistry
Record number
1305249
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