Title of article
Synthesis and antiproliferative activity of clausine E, mukonine, and koenoline bioisosteres Original Research Article
Author/Authors
François Liger، نويسنده , , Florence Popowycz، نويسنده , , Thierry Besson، نويسنده , , Laurent Picot، نويسنده , , Carlos M. Galmarini، نويسنده , , Benoît Joseph، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
5
From page
5615
To page
5619
Abstract
Aza-analogues of clausine E, mukonine and koenoline were prepared from 1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxaldehyde and their antiproliferative activity was evaluated against miscellaneous cancer cell lines and compared to those obtained with clausine E and mukonine.
Keywords
Sulfamides , rational design , Anticonvulsant , Bioisosteres , Pharmacophore
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2007
Journal title
Bioorganic and Medicinal Chemistry
Record number
1305958
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