Title of article :
Synthesis, DNA binding, and cytotoxicity studies of pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates Original Research Article
Author/Authors :
Ahmed Kamal، نويسنده , , R. Ramu، نويسنده , , Venkatesh Tekumalla، نويسنده , , G.B. Ramesh Khanna، نويسنده , , Madan S. Barkume، نويسنده , , Aarti S. Juvekar، نويسنده , , Surekha M. Zingde، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2007
Abstract :
A series of pyrrolo[2,1-c][1,4]benzodiazepine-anthraquinone conjugates have been prepared and evaluated for their DNA binding ability as well as anticancer activity. Some of these molecules have shown significant anticancer activity in a number of cancer cell lines.
Keywords :
Pyrrolobenzodiazepines , DNA binding , Anticancer activity , Anthraquinones
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry
