Ratiometric multimodal chemosensors based on cubic silsesquioxanes for monitoring solvent polarity Original Research Article

We report the multi-functionalized cubic silsesquioxane (POSS) as the ratiometric multimodal chemosensors for monitoring solvent polarity with fluorescence and 19F NMR. The alteration of the dispersion state of the modified POSS by changing solvent polarity can be reflected into the orthogonal signal responses for the fluorescence and 19F NMR. In addition, the ratiometric dual monitoring for the enzymatic reaction was performed using the POSS-based chemosensor.