Title of article
Conjugates of gonadotropin releasing hormone (GnRH) with carminic acid: Synthesis, generation of reactive oxygen species (ROS) and biological evaluation Original Research Article
Author/Authors
We synthesized two carminic acid (7-?-d-glucopyranosyl-9، نويسنده , , 10-dihydro-3، نويسنده , , 5، نويسنده , , 6، نويسنده , , 8-tetrahydroxy-1-methyl-9، نويسنده , , 10-dioxo-2-anthracene carboxlic acid، نويسنده , , CA)-GnRH conjugates to be used as a model for potential photoactive targeted compounds. CA was conjugated to the ?-amino group of [d-Lys6]Gn، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
10
From page
6789
To page
6798
Abstract
We synthesized two carminic acid (7-α-d-glucopyranosyl-9,10-dihydro-3,5,6,8-tetrahydroxy-1-methyl-9,10-dioxo-2-anthracene carboxlic acid, CA)-GnRH conjugates to be used as a model for potential photoactive targeted compounds. CA was conjugated to the ε-amino group of [d-Lys6]Gn
Keywords
Anthraquinone , GnRH , Carminic acid , Drug targeting , Reactive oxygen species (ROS) , Photosensitizer
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2008
Journal title
Bioorganic and Medicinal Chemistry
Record number
1306286
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