Title of article
Synthesis of a series of caffeic acid phenethyl amide (CAPA) fluorinated derivatives: Comparison of cytoprotective effects to caffeic acid phenethyl ester (CAPE) Original Research Article
Author/Authors
John Yang، نويسنده , , Gwendolyn A. Marriner، نويسنده , , Xinyu Wang، نويسنده , , Phillip D. Bowman، نويسنده , , Sean M. Kerwin، نويسنده , , Salomon Stavchansky، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
7
From page
5032
To page
5038
Abstract
A series of catechol ring-fluorinated derivatives of caffeic acid phenethyl amide (CAPA) were synthesized and screened for cytoprotective activity against H2O2 induced oxidative stress in human umbilical vein endothelial cells (HUVEC). CAPA and three fluorinated analogs were found to be significantly cytoprotective when compared to control, with no significant difference in cytoprotection between caffeic acid phenethyl ester (CAPE) and CAPA.
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2010
Journal title
Bioorganic and Medicinal Chemistry
Record number
1306701
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