Title of article :
Square pyramidal copper(II) complexes with forth generation fluoroquinolone and neutral bidentate ligand: Structure, antibacterial, SOD mimic and DNA-interaction studies Original Research Article
Author/Authors :
Mohan N. Patel، نويسنده , , Pradhuman A. Parmar، نويسنده , , Deepen S. Gandhi، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2010
Abstract :
Coordination of neutral bidentate ligand to copper ion in combination with gatifloxacin have been focused in this article. The effect of complexation reflects antibacterial activity, DNA interaction and SOD mimic activity of individual greatly. The geometry at the central metal ion provides a site for binding of superoxide anion responsible for better SOD mimic behaviour.
Keywords :
Gatifloxacin , Antimicrobial , pUC19 , Superoxide anion , IC50
Journal title :
Bioorganic and Medicinal Chemistry
Journal title :
Bioorganic and Medicinal Chemistry