• Title of article

    Square pyramidal copper(II) complexes with forth generation fluoroquinolone and neutral bidentate ligand: Structure, antibacterial, SOD mimic and DNA-interaction studies Original Research Article

  • Author/Authors

    Mohan N. Patel، نويسنده , , Pradhuman A. Parmar، نويسنده , , Deepen S. Gandhi، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2010
  • Pages
    9
  • From page
    1227
  • To page
    1235
  • Abstract
    Coordination of neutral bidentate ligand to copper ion in combination with gatifloxacin have been focused in this article. The effect of complexation reflects antibacterial activity, DNA interaction and SOD mimic activity of individual greatly. The geometry at the central metal ion provides a site for binding of superoxide anion responsible for better SOD mimic behaviour.
  • Keywords
    Gatifloxacin , Antimicrobial , pUC19 , Superoxide anion , IC50
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Serial Year
    2010
  • Journal title
    Bioorganic and Medicinal Chemistry
  • Record number

    1307121