Title of article
Square pyramidal copper(II) complexes with forth generation fluoroquinolone and neutral bidentate ligand: Structure, antibacterial, SOD mimic and DNA-interaction studies Original Research Article
Author/Authors
Mohan N. Patel، نويسنده , , Pradhuman A. Parmar، نويسنده , , Deepen S. Gandhi، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
9
From page
1227
To page
1235
Abstract
Coordination of neutral bidentate ligand to copper ion in combination with gatifloxacin have been focused in this article. The effect of complexation reflects antibacterial activity, DNA interaction and SOD mimic activity of individual greatly. The geometry at the central metal ion provides a site for binding of superoxide anion responsible for better SOD mimic behaviour.
Keywords
Gatifloxacin , Antimicrobial , pUC19 , Superoxide anion , IC50
Journal title
Bioorganic and Medicinal Chemistry
Serial Year
2010
Journal title
Bioorganic and Medicinal Chemistry
Record number
1307121
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