Author/Authors :
Sheikh، N نويسنده Dept. of Biochemistry & Nutrition, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran , , Goodarzi، MT نويسنده Dept. of Biochemistry & Nutrition, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran. , , Bab Al-Havaejee، H نويسنده Dept. of Urology, School of Medicine, Hamadan University of Medical Sciences, Iran , , Safari، MR نويسنده Laboratory Medicine Department, Paramedicine Faculty, Hamadan University of Medical Sciences & Health Services, Hamadan, Iran Safari, MR , Amiri ، I نويسنده Dept. of Anatomy, School of Medicine, Hamadan University of Medical Sciences, Iran , , Najafi، R نويسنده Medical Technology, Hamadan University of Medical Sciences, Hamadan, Iran , , Hadeie ، J نويسنده Medical Technology, Hamadan University of Medical Sciences, Hamadan, Iran ,
Abstract :
Background: To determine any correlation between infertility and semen quality with concentrations of L-carnitine in human seminal plasma.
Methods: This case-control study performed in Fatemieh Hospital in Hamadan, Iran. Seminal plasma of 72 infertile men and 80 men with proved fertility as a control group was investigated and L-car-nitine level was determined using UV enzymatic test at 340 nm.
Results: The concentration of L-carnitine was significantly lower in the infertile group compared with con trol group (80.59?56.43 mg/l versus 108.43?42.26 mg/l; P= 0.0009). There was also a statistically signifi cant positive correlation between seminal plasma L-carnitine concentration, total sperm count, and the percentage of motile sperm (P= 0.0009, and P= 0.0000, respectively).
Conclusion: These finding suggest that the determination of seminal plasma L-carnitine level may be a useful test in evaluation of male infertility.
