Title of article :
The Effect of Low Tidal Volume Ventilation during Cardiopulmonary Bypass on Postoperative Pulmonary Function
Author/Authors :
Davoudi، Maryam نويسنده , , Farhanchi، Afshin نويسنده , , Moradi ، Ahmad Reza نويسنده Virology Research Center, NRITLD, Shahid Beheshti University M.C., TEHRAN- IRAN , , Bakhshaei، Mohammad Hosein نويسنده Ekbatant Hospital, Hamadan University of Medical Sciences, Hamadan, Iran. , , Safarpour، Gholamreza نويسنده Ekbatant Hospital, Hamadan University of Medical Sciences, Hamadan, Iran. ,
Issue Information :
فصلنامه با شماره پیاپی 0 سال 2010
Pages :
4
From page :
128
To page :
131
Abstract :
Background: Postoperative pulmonary dysfunction is one of the most frequent complications after cardiac surgery and it is believed to result from the use of cardiopulmonary bypass (CPB). In this study, we investigated the effect of low tidal volume ventilation during CPB on postoperative gas exchange and lung mechanics. Methods: This prospective randomized study included 100 patients undergoing elective coronary artery bypass grafting. In 50 patients, low tidal volume ventilation [tidal volume (TV) = 3 ml/kg, respiratory rate (RR) = 12/min, fraction of inspiratory oxygen (FIO2)= 1.0, positive end expiratory pressure (PEEP) = 5 cmH2O] was applied during CPB (group I); and in the other 50 patients (group II), the lungs were open to the atmosphere without ventilation. Measurements were taken preoperatively, after CPB, and before discharge. Results: Post-bypass PaO2 (just after CPB 85 versus75) was higher significantly in group I (P value < 0.05). Decrease in postoperative forced expiratory volume in 1 second (25% versus 30%) and forced vital capacity (32% versus 35%) was less significant in group I. Also, time to extubation (5 hrs versus 5.5 hrs) was shorter in group I. Conclusion: Continued low tidal volume ventilation during CPB improved post-bypass oxygenation and lung mechanics.
Journal title :
The Journal of Tehran University Heart Center (JTHC)
Serial Year :
2010
Journal title :
The Journal of Tehran University Heart Center (JTHC)
Record number :
1314604
Link To Document :
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