Title of article :
Cleavage of the C–N bond of a peptide group by a copper(II)-peroxide adduct with an η1-coordination mode
Author/Authors :
Satoshi Nishino، نويسنده , , Mami Kunita، نويسنده , , Yoshiyuki Kani، نويسنده , , Shigeru Ohba، نويسنده , , Hideaki Matsushima، نويسنده , , Tadashi Tokii، نويسنده , , Yuzo Nishida، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2000
Abstract :
We have obtained clear evidence that a copper(II)-peroxide adduct with an η1-coordination mode can cleave the C–N bond of a peptide group and hydroxylate the alkyl group nearby; this may provide helpful information for elucidation of the reaction mechanism of PAM, peptidylglycine α-amidating monooxygenase.
Keywords :
Model reaction for PAM enzyme , Copper(II)-peroxide adduct , ?1-Coordination mode , Cleavage of protein
Journal title :
Inorganic Chemistry Communications
Journal title :
Inorganic Chemistry Communications
