Solvolysis-controlled chirality resolution through metal-chelation effect: from racemate to homochiral one-dimensional copper helicate

Through controlling the in-situ methoxyl addition that consequently switches the metal-chelation effect, a one-dimensional helical coordination polymer (1) and a chiral congeners (P-2 and M-2) were prepared, the 41 helice of opposite chirality in complex 1 are stacked alternately to form a racemate, while the 41 and 43 helices in the other are assembled homochirally by metal-chelation effect to generate a conglomerate, P-2 and M-2, respectively.