• Title of article

    Structural characterization and SOD activity of copper–oxaprozinate

  • Author/Authors

    Sabari Dutta، نويسنده , , Subhash Padhye، نويسنده , , Vickie Mckee، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2004
  • Pages
    4
  • From page
    1071
  • To page
    1074
  • Abstract
    SOD activity of the diaryl substituted heterocyclic COX-2 inhibitor, viz. oxaprozin (2), is synergistically enhanced upon copper conjugation compared to analogous copper compounds of established COX-1 inhibitors like aspirin (1) and ibuprofen (3). A “paddle-wheel” structure is reported for the dimeric copper complex of oxaprozin.
  • Keywords
    Oxaprozin , Copper conjugation , SOD activity , X-ray crystal structure , COX inhibitors
  • Journal title
    Inorganic Chemistry Communications
  • Serial Year
    2004
  • Journal title
    Inorganic Chemistry Communications
  • Record number

    1316546