Copper-assisted oxidative coupling of primary alcohol and hydrazone: A novel function model of galactose oxidase

Treatments of the MeOH, EtOH and PrOH solutions of 2-acetylpyridine, hydrazine and CuII salts (in molar ratio 2:3:2) afforded respectively the complexes, [CuII(HL)(Cl)](SO3CF3)H2O (1), [CuII(MeL)(H2O)](ClO4)2 (2) and [CuII(EtL)](Cl)](ClO4) (3) (L = bis-(methyl, 2-pyridyl ketone hydrazonyl)methine), in which the ligands, HL, MeL and EtL are formed in situ from oxidative couplings of alcohols and hydrazones.