Title of article
Light induced DNA scission by a luminescent mixed-ligand uranyl complex
Author/Authors
Sanjib Das، نويسنده , , C. Madhavaiah، نويسنده , , Sandeep Verma، نويسنده , , Sujit K. Ghosh and Parimal K. Bharadwaj ، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
5
From page
548
To page
552
Abstract
Efficient cleavage of supercoiled pBR322 DNA by X-ray crystallographically characterized complex, [UO2(phen)(aba)(OC2H5)] (phen = 1,10-phenanthroline; aba = 4-dimethylamino benzoate) has been observed on irradiation with UV (350 nm) or visible light without any external additives through a mechanistic pathway involving singlet oxygen. This complex having 1,10-phenanthroline as an intercalator/binder to supercoiled DNA and N,N-(dimethylamino)benzoate as a chromophore.
Keywords
Uranyl complex , Plasmid DNA , photocleavage , Physiological pH , Homogeneous catalyst
Journal title
INORGANICA CHIMICA ACTA
Serial Year
2006
Journal title
INORGANICA CHIMICA ACTA
Record number
1323266
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