Author/Authors :
Sleightholm، نويسنده , , Lee and Zambre، نويسنده , , Ajit and Chanda، نويسنده , , Nripen and Afrasiabi، نويسنده , , Zahra and Katti، نويسنده , , Kattesh and Kannan، نويسنده , , Raghuraman، نويسنده ,
Abstract :
Gold–thioguanine nanoconjugates (AuNP–TG) of size 3–4 nm were synthesized and the ratio between gold and 6-thioguanine (TG) was estimated as ∼1:1.5 using a cyanide digestion method and confirmed by flame atomic absorption spectroscopic analysis. AuNP–TG constructs showed high in vitro stability under different pH conditions and biologically relevant solutions for a period of 24 h. Reaction of AuNP–TG with europium or platinum salts resulted in the formation of organized self-assembled metallo-networks.
Keywords :
Gold nanoparticles , Europium , Platinum , Thioguanine , Nanomedicine , ligands
