Boron clusters-based metallodendrimers

This review includes a compilation of different types of star-shaped molecules and dendrimers decorated with boron clusters, carboranes or metallacarboranes, at their periphery. Dendrimeric platforms, such as PAMAM, carbosilane, poly(aryl-ether), among others, have been functionalized with a different number of small metallacarboranes, nido-carboranes or cobaltabisdicarbollide clusters following diverse methodologies. In general, all these structures are high-boron content molecules, and for those that carry nido-carboranes and alkaline metals, are also soluble in water. Most of these compounds have been proposed as highly promising boron delivery agents for the BNCT of tumors, particularly for malignant brain tumors. Nevertheless, other applications such as catalysts, optoelectronic devices, drug delivery systems, and others can be envisaged.